The Substance (2024)

A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.

10 Kinolab Clips

A scientist injects an egg with the substance and it produces another yolk.

Duration: 00:00:53
Timestamp: 00:01:07
Contributor: Sid Bell

Elisabeth (Demi Moore) overhears that Harvey (Dennis Quaid) is seeking a replacement for her.

Duration: 00:03:35
Timestamp: 00:04:26
Contributor: Sid Bell

Elisabeth (Demi Moore) gets into a car accident. While at the doctor's office, a young nurse (Robin Greer) gives her an extra examination.

Duration: 00:02:21
Timestamp: 00:09:23
Contributor: Sid Bell

Elisabeth (Demi Moore) watches an advertisement for The Substance.

Duration: 00:01:54
Timestamp: 00:13:27
Contributor: Sid Bell

Elisabeth (Demi Moore) activates The Substance for the first time and births Sue (Margaret Qualley) out of her back.

Duration: 00:11:31
Timestamp: 00:22:00
Contributor: Sid Bell

Elisabeth (Demi Moore) and Sue (Margaret Qualley) switch back for the first time.

Duration: 00:03:09
Timestamp: 00:41:00
Contributor: Sid Bell

Elisabeth (Demi Moore) tries to terminate Sue (Margaret Qualley), but, on second thought, brings her back to life.

Duration: 00:09:30
Timestamp: 00:41:50
Contributor: Sid Bell

Sue (Margaret Qualley) extends her time by one day, which, by the rules of The Substance, is not allowed.

Duration: 00:05:08
Timestamp: 00:55:26
Contributor: Sid Bell

Monstro Elisasue (Margaret Qualley) performs for a crowd, but chaos ensues.

Duration: 00:08:28
Timestamp: 02:02:45
Contributor: Sid Bell

The remains of Monstro Elisasue (Margaret Qualley/Demi Moore) melt away on Elisabeth Sparkle's Hollywood star.

Duration: 00:03:01
Timestamp: 02:11:13
Contributor: Sid Bell